IL1 beta antibody (HL1421)

Clone Name: HL1421

Light Chain: Kappa

Application Note: IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 31

Specificity/Sensitivity: The use of GTX636887 for mouse is based on IHC-P testing. For WB using mouse samples, we recommend GTX74034.

Form: Liquid

Buffer (with preservative): PBS, no preservative.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]

Uniprot ID: P01584

Antigen Species: Human

Immunogen: Recombinant protein encompassing a sequence within the center region of human IL1 beta. The exact sequence is proprietary.

Purification: Affinity purified by Protein A.

Conjugation: Unconjugated

Full Name: interleukin 1 beta

• Artikelnummer: GTX636887-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX636887-100
• Green Labware: Nein
• Verpackungseinheit: 100 μl
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunohistochemistry (paraffin), Western Blotting, ELISA, Immunocytochemistry
• Isotyp: IgG
• Human Gene ID: 3553
• Wirt: Rabbit