IL6ST Polyclonal Antibody, Rabbit

Abbreviation: IL6ST

Target Synonym: IL6ST;CD130;CDW130;GP130;IL-6RB

Conjugation: Unconjugated

UNIProt ID: P40189

Background: The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human IL6ST

Dilution: WB 1:500-1:2000,IF 1:50-1:200

• Artikelnummer: ELSE-AB-93225-200
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-E-AB-93225-200
• Green Labware: Nein
• Verpackungseinheit: 200 µl
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Polyclonal
• Methode: Immunofluorescence, Western Blotting
• Isotyp: IgG
• Wirt: Rabbit