IL6ST Polyclonal Antibody, Rabbit

IL6ST Polyclonal Antibody, Rabbit
Artikelnummer
ELSE-AB-93225-60
Verpackungseinheit
60 µl
Hersteller
Elabscience Biotechnology

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Abbreviation: IL6ST

Target Synonym: IL6ST;CD130;CDW130;GP130;IL-6RB

Conjugation: Unconjugated

UNIProt ID: P40189

Background: The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human IL6ST

Dilution: WB 1:500-1:2000,IF 1:50-1:200
Mehr Informationen
Artikelnummer ELSE-AB-93225-60
Hersteller Elabscience Biotechnology
Hersteller Artikelnummer ELA-E-AB-93225-60
Green Labware Nein
Verpackungseinheit 60 µl
Mengeneinheit STK
Reaktivität Human, Mouse (Murine), Rat (Rattus)
Klonalität Polyclonal
Methode Immunofluorescence, Western Blotting
Isotyp IgG
Wirt Rabbit
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