Integrin alpha 6 antibody (NKI-GoH3) (PE)

Clone Name: NKI-GoH3

Application Note: FACS: 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 127

Form: Liquid

Buffer (with preservative): PBS, 1% BSA, 5% Sucrose, 0.09% Sodium Azide.

Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)

Background: The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

Uniprot ID: P23229

Antigen Species: Mouse

Immunogen: BALB/c mouse mammary tumor cells

Purification: Purified by affinity chromatography

Conjugation: PE

Full Name: integrin subunit alpha 6

• Artikelnummer: GTX76413-08-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX76413-08-100
• Verpackungseinheit: 100 test
• Mengeneinheit: PAK
• Reaktivität: Human, Mouse (Murine), Cynomolgus Monkey (Primate), Pig (Porcine), Sheep (Ovine), Dog (Canine)
• Klonalität: Monoclonal
• Methode: Flow Cytometry
• Isotyp: IgG2a
• Human Gene ID: 3655
• Wirt: Rat
• Konjugat: Conjugated, PE (Phycoerythrin)