Clone Name: IFNA/6689
Light Chain: Kappa
Application Note: WB: 1-2ug/ml. IHC-P: 1-2ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Specificity/Sensitivity: This antibody is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2.
Form: Liquid
Buffer (with preservative): 10mM PBS, 0.05% BSA, 0.05% sodium azide.
Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded cytokine is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral, antiproliferative and immunomodulatory properties. This cytokine, like other type I interferons, binds a plasma membrane receptor made of IFNAR1 and IFNAR2 that is ubiquitously expressed, and thus is able to act on virtually all body cells. This cytokine is upregulated in preeclamptic placentas and is thought to be a mediator of preeclampsia. [provided by RefSeq, Aug 2020]
Uniprot ID: P01562
Antigen Species: Human
Immunogen: Recombinant human IFNA1 protein.
Purification: Protein A/G purified
Conjugation: Unconjugated
Full Name: interferon alpha 1