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JNK (phospho Thr183/Tyr185) antibody
JNK (phospho Thr183/Tyr185) antibody
Artikelnummer
GTX133934-S-25
Verpackungseinheit
25 μl
Hersteller
GeneTex
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Application Note: WB: 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 48
Form: Liquid
Buffer (with preservative): PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
Concentration: 1.09 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016]
Uniprot ID: P45983
Antigen Species: Human
Immunogen: Carrier-protein conjugated synthetic peptide surrounding phospho Thr183/Tyr185 of human JNK. The exact sequence is proprietary.
Purification: Purified by antigen-affinity chromatography.
Conjugation: Unconjugated
Full Name: mitogen-activated protein kinase 8
Calculated MW: 48
Form: Liquid
Buffer (with preservative): PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
Concentration: 1.09 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016]
Uniprot ID: P45983
Antigen Species: Human
Immunogen: Carrier-protein conjugated synthetic peptide surrounding phospho Thr183/Tyr185 of human JNK. The exact sequence is proprietary.
Purification: Purified by antigen-affinity chromatography.
Conjugation: Unconjugated
Full Name: mitogen-activated protein kinase 8
| Artikelnummer | GTX133934-S-25 |
|---|---|
| Hersteller | GeneTex |
| Hersteller Artikelnummer | GTX133934-S-25 |
| Green Labware | Nein |
| Verpackungseinheit | 25 μl |
| Mengeneinheit | STK |
| Reaktivität | Human, Mouse (Murine), Fruit Fly (Drosophila Melanogaster) |
| Klonalität | Polyclonal |
| Methode | Immunohistochemistry (paraffin), Western Blotting |
| Isotyp | IgG |
| Human Gene ID | 5599 |
| Wirt | Rabbit |
| Produktinformation (PDF) | Download |
| MSDS (PDF) | Download |
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