JNK1/2/3 Polyclonal Antibody, Rabbit

Abbreviation: JNK1/2/3

Conjugation: Unconjugated

UNIProt ID: P45983/P45984/P53779

Background: JNK belongs to MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. JNK is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation.JNK is expressed as ten different isoforms due to differential mRNA splicing. The predominant forms are JNK1,JNK2,and JNK3

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human JNK1/2/3

Dilution: WB 1:500-1:2000,IHC 1:50-1:200,IF 1:50-1:200,IP 1:50-1:100

• Artikelnummer: ELSE-AB-93242-120
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-E-AB-93242-120
• Green Labware: Nein
• Verpackungseinheit: 120 µl
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Polyclonal
• Methode: Immunofluorescence, Immunoprecipitation, Western Blotting, Immunohistochemistry
• Isotyp: IgG
• Wirt: Rabbit