Ketanserin tartrate, CAS 83846-83-7

Serotonin 5HT2A Antagonist
Artikelnummer
STRSIH-618-5MG
Verpackungseinheit
5 mg
Hersteller
Stressmarq Biosciences

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Product Type: Antagonist

CAS No.: 83846-83-7

MolecularFormula: C22H22FN3O3 • C4H6O6

Molecular Weight: 545,5

Source: Synthetic

Purity: >98% (HPLC); NMR (Conforms)

Solubility: May be dissolved in DMSO (30 mg/ml); or Water (5 mg/ml)

Appearance: White powder

PubChem CID: 135348

Scientific Background: A selective serotonin 5-HT2A receptor antagonist (IC50 = 6.3 nM) (1). Also exhibits significant selectivity for the human 5-HT1Dα receptor (2). Was shown to be effective for the treatment of hypertension following coronary artery surgery (3). It has been used to disrupt the hallucinogenic effects of psilocybin and to explore cognitive effects of the 5-HT2A receptor (4).

References: 1. Leysen JE., et al. (1981) Life Sci. 28:1015.2. Zgombick JM., et al. (1995) Eur. J. Pharmacol. 291:9.3. Vandenbroucke G., et al.(1994) J. Cardiothorac. Vasc. Anesth. 8: P324.4. Quednow BB.,et al. (2012) Neuropsychopharmacology. 37:630.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Mehr Informationen
Artikelnummer STRSIH-618-5MG
Hersteller Stressmarq Biosciences
Hersteller Artikelnummer SIH-618-5MG
Verpackungseinheit 5 mg
Mengeneinheit STK
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