Ki-67 (Proliferating Cell Marker)(MKI67/2461), 1mg/mL

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Description: Ki-67 antigen is a nuclear, non-histone protein that is present in all stages of the cell cycle except G0. This characteristic makes Ki-67 an excellent marker for proliferating cells and is commonly used as one of the prognostic factors in cancer studies. A correlation has been demonstrated between Ki-67 index and the histo-pathological grade of neoplasms. Assessment of Ki-67 expression in renal and ureter tumors shows a correlation between tumor proliferation and disease progression, thus making it possible to differentiate high-risk patients. Ki-67 expression may also prove to be important for distinguishing between malignant and benign peripheral nerve sheath tumors. Ki-67 labeling index has been shown to be a prognostic marker in a number of neoplasms including grade II astrocytoma, oligodendroglioma, colon carcinoma, and breast carcinoma. In general, Ki-67 is a good marker of proliferating cell populations. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Mus musculus (mouse)

Clone: MKI67/2461

Entrez Gene ID: 4288

Immunogen: Recombinant fragment of human Ki67 protein (around aa 2293-2478) (exact sequence is proprietary)

Verified AB Applications: Flow (intracellular) (verified)/IF (verified)/IHC (FFPE) (verified)/WB (verified)

Z-Antibody Applications: Flow, intracellular (verified)/IF (verified)/IHC, FFPE (verified)/WB (verified)

• Artikelnummer: BTMBNUM2461-50
• Hersteller: Biotium
• Hersteller Artikelnummer: BNUM2461-50
• Verpackungseinheit: 50 uL
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Western Blotting, Flow Cytometry, Immunohistochemistry
• Isotyp: IgG1 kappa
• Wirt: Mouse
• Konjugat: Unconjugated