KLD-12 (TFA)

Product Description: KLD-12 TFA is the TFA salt form of KLD-12 (HY-P2263). KLD-12 TFA is a self a 12-residue self-assembling peptide that is used in tissue-engineering. KLD-12 TFA combined with SDF-1 self-assembled polypeptide enhances chondrogenic differentiation of bone marrow stromal cells (BMSCs). KLD-12 TFA hydrogel can fill full-thickness osteochondral defects in situ and improve cartilage repair[1][2][3].

Applications: COVID-19-immunoregulation

Formula: C68H122N16O19.xC2HF3O2

References: [1]Cao M, et al., Self-Assembled KLD-12/SDF-1 Polypeptide Promotes Differentiation and Migration of BMSCs via the Wnt/β-catenin Signaling Pathways. Protein Pept Lett. 2022;29(10):851-858. /[2]Tripathi JK, et al., Variants of self-assembling peptide, KLD-12 that show both rapid fracture healing and antimicrobial properties. Biomaterials. 2015 Jul;56:92-103. /[3]Kisiday J, Jet al., Self-assembling peptide hydrogel fosters chondrocyte extracellular matrix production and cell division: implications for cartilage tissue repair. Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):9996-10001.

Molecular Weight: 1467.79 (free base)

Compound Purity: 95.22

Research Area: Inflammation/Immunology

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Others

• Artikelnummer: MEXHY-P2263A-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P2263A-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK