Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16 (CDH16/1532R), 1mg/mL

Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16 (CDH16/1532R), 1mg/mL
Artikelnummer
BTMBNUM1532-50
Verpackungseinheit
50 uL
Hersteller
Biotium

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Description: This MAb recognizes a protein of 130 kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Oryctolagus cuniculus (domestic rabbit)

Clone: CDH16/1532R

Entrez Gene ID: 1014

Immunogen: Recombinant human full-length CDH16 protein

Verified AB Applications: Flow (verified)/IHC (FFPE) (verified)/WB (verified)

Z-Antibody Applications: Flow (verified)/IHC, FFPE (verified)/WB (verified)
Mehr Informationen
Artikelnummer BTMBNUM1532-50
Hersteller Biotium
Hersteller Artikelnummer BNUM1532-50
Verpackungseinheit 50 uL
Mengeneinheit STK
Reaktivität Human, Mouse (Murine), Rat (Rattus)
Klonalität Recombinant
Methode Western Blotting, Flow Cytometry, Immunohistochemistry
Isotyp IgG kappa
Wirt Rabbit
Konjugat Unconjugated
Produktinformation (PDF) Download
MSDS (PDF) Download