KT5720, CAS 108068-98-0

PKA kinase inhibitor

Product Type: Inhibitor

CAS No.: 108068-98-0

MolecularFormula: C32H31N3O5

Molecular Weight: 537,6

Source: Synthetic

Purity: ≥98% (TLC)

Solubility: Soluble in methanol: clear colorless solution at 5 mg/ml

Appearance: White powder

PubChem CID: 3844

Scientific Background: KT5720 is a potent and selective inhibitor of protein kinase A (PKA). This compound blocks PKA signaling through competitive inhibition. It causes no significant effect on protein kinase C (PKC), protein kinase G (PKG) or myosin light chain kinase (mlCK). KT5720 has been shown to reversibly arrests human skin fibroblasts in the G1 phase. It is cell permeable.

References: 1. Kase H., et al. (1987) Biochem. Biophys. Res. Comm. 142(2): 436–440.2. Gadbois D.M., Crissman H.A., Tobey R.A., & Bradbury E.M. (1992) Pro. Na. Aca. Sci. USA. 89(18): 8626–8630.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSIH-457-100UG
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SIH-457-100UG
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK