Product Description
Lacromin® is a high-purity recombinant human lactoferrin (rLF) designed to enhance cell growth, improve viability, and protect against apoptosis in cell culture applications. By activating cellular signaling pathways similar to Insulin-Like Growth Factor (IGF), Lacromin provides a chemically defined, serum-free alternative to traditional lactoferrin sources, optimizing growth conditions for CHO, HEK, primary, and pluripotent cell types.
Manufactured in an ISO 9001:2015-certified, cGMP-compliant facility in the United States, Lacromin ensures batch-to-batch consistency, regulatory compliance, and pathogen-free safety, making it ideal for biopharmaceutical production, cell therapy, and regenerative medicine.
Advantages
- Optimized for Serum-Free, Animal-Origin-Free Cell Culture
- Fully recombinant, blood-free human lactoferrin, providing a stable and controlled supplement for cell culture.
- Activates IGF-like signaling, enhancing cell proliferation and survival.
- Prevents apoptosis in select cell types, improving viability and long-term culture success.
- Animal-Origin-Free Assurance
- 100% chemically defined and animal-origin-free (AOF) – eliminating batch variability and regulatory risks associated with plasma-derived lactoferrin.
- Manufactured using a non-animal, non-human host system, ensuring purity and reproducibility.
- Raw materials, manufacturing equipment, and packaging are fully animal-free, aligning with ethical and regulatory standards.
- Manufactured in the United States
- Produced in a tertiary-level, ISO 9001:2015-certified facility in the USA.
- Complete supply and manufacturing chain is owned and operated by InVitria, ensuring unmatched traceability and quality control.
- Batch-to-batch consistency for reliable integration into cGMP cell culture workflows.
- Ready-to-Use Lyophilized Format
- Supplied as a lyophilized powder, providing long-term stability and easy reconstitution.
- Flexible formulation to support a wide range of cell culture applications.
- Eliminates variability associated with serum-derived lactoferrin, enabling chemically defined media development.
Applications
- Cell Culture & Bioproduction
- Enhances CHO and HEK cell proliferation, supporting biopharmaceutical and vaccine production.
- Improves cell viability in chemically defined, serum-free media.
- Stem Cell Expansion & Regenerative Medicine
- Supports pluripotent and primary cell cultures, ensuring high viability and growth rates.
- Provides a defined, animal-free alternative for long-term cell culture and differentiation studies.
- Immune Cell Culture & Therapeutic Development
- Enhances immune cell survival, reducing apoptosis in T cell and NK cell cultures.
- Supports cellular activation and expansion in immunotherapy applications.
- Gene Therapy & Vaccine Production
- Stabilizes cell cultures used for viral vector production, optimizing yields and process efficiency.
- Ensures greater consistency in biomanufacturing workflows.
Technical Specifications
- Formulation: Lyophilized recombinant human lactoferrin
- Manufacturing: Produced in a state-of-the-art, ISO 9001:2015-certified facility in the USA
- Quality Assurance:
- Fully recombinant and animal-origin-free production system
- Stringent quality control processes ensure high batch-to-batch consistency
- Regulatory Compliance & Safety:
- cGMP-compliant manufacturing
- Plasma-free, pathogen-free, and chemically defined
- Aligned with regulatory expectations for biopharmaceutical, regenerative medicine, and vaccine production applications
Why Choose Lacromin?
Lacromin is a high-performance alternative to serum-derived lactoferrin, offering unparalleled purity, stability, and regulatory compliance. Whether used for cell therapy, biopharmaceutical manufacturing, or regenerative medicine, Lacromin provides a safe, scalable, and animal-free solution for industrial and research applications.