LPA1 Polyclonal Antibody

Formulation: 500 µl of peptide affinity-purified polyclonal antibody

Immunogen: Synthetic peptide from the C-terminal cytoplasmic region of human protein LPA1

Shelf life (days): 1095

Notes: LPA1 (also known as EDG-2) is one of four known LPA receptors (LPA1-4).{13001} LPA1-3 are part a family of G protein-coupled receptors that share identity to the sphingosine-1-phosphate receptors (S1P1-5).{11049} LPA1 couples with three types of G proteins, Gi/o, Gq, and G12/13 to induce a range of cellular responses including activation of phospholipase C, multiple kinases, the serum response element and cell proliferation.{11808,12477} LPA1 mRNA is detected a wide range of tissues and cells including brain, heart, small intestine, spleen, testis, kidney, HeLa cells, and A549 cells.{11810,12912} Mouse and human LPA1 have 364 amino acids with an estimated molecular weight of 41 kDa.{12477} Cayman’s LPA1 Polyclonal Antibody detects the protein from several species from 43-50 kDa, suggesting heterogeneous LPA1 post-translational modifications in distinct cells.

• Artikelnummer: CAY10005280-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 10005280-500
• Green Labware: Nein
• Verpackungseinheit: 1 ea (500 µl)
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Polyclonal
• Methode: Immunofluorescence, Western Blotting, Immunohistochemistry, Immunocytochemistry
• Wirt: Rabbit