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Encompassing Amino Acids: 2-824 (end)
Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Assay Conditions: 50 mM HEPES, 150 mM NaCl, 1M Na Citrate, 0.05% CHAPS, 1 mM DTT, 100 µM substrate (Z-VRPR-AMC), incubate at room temperature for 30 min.Fluorescence intensity is measured at exc/em 360/460nm.
Description: Human MALT1 also known as IMD12, MLT, MLT1, PCASP1, and MALT1 paracaspase, GenBank Accession No. NM_006785, a.a. 2-824 (end), and expressed in HEK293 cells. MW = 93 kDa.
Format: Aqueous buffer solution
Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, 100µg/ml FLAG peptide and 20% glycerol.
Genbank: NM_006785
Storage Stability: At least 6 months at -80°C.
Tags: N-terminal FLAG-Tag
Uniprot: Q9UDY8
Biosafety Level: Not applicable (BSL-1)
References: 1. Lijun, S., et al., Molecular Cell. 2004. May 14;3: 289-301.2. Lucas, P., et al., JBC. 2001. June 276: 19012-19019.