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MAN1B1 antibody
MAN1B1 antibody
Artikelnummer
GTX03414-100
Verpackungseinheit
100 μl
Hersteller
GeneTex
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Application Note: WB: 1:500 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 80
Form: Liquid
Buffer (with preservative): PBS, 50% Glycerol, 0.02% sodium azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Dec 2011]
Uniprot ID: Q9UKM7
Antigen Species: Human
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human MAN1B1 (NP_057303.2).
Purification: Purified by affinity chromatography
Conjugation: Unconjugated
Full Name: mannosidase alpha class 1B member 1
Calculated MW: 80
Form: Liquid
Buffer (with preservative): PBS, 50% Glycerol, 0.02% sodium azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Dec 2011]
Uniprot ID: Q9UKM7
Antigen Species: Human
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human MAN1B1 (NP_057303.2).
Purification: Purified by affinity chromatography
Conjugation: Unconjugated
Full Name: mannosidase alpha class 1B member 1
| Artikelnummer | GTX03414-100 |
|---|---|
| Hersteller | GeneTex |
| Hersteller Artikelnummer | GTX03414-100 |
| Green Labware | Nein |
| Verpackungseinheit | 100 μl |
| Mengeneinheit | STK |
| Reaktivität | Human, Mouse (Murine), Rat (Rattus) |
| Klonalität | Polyclonal |
| Methode | Western Blotting |
| Isotyp | IgG |
| Human Gene ID | 11253 |
| Wirt | Rabbit |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
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Gernot Ensinger, M.Sc.
Laurent Haze
