Formulation: A solid
Formal Name: 5-(1,3-benzodioxol-5-yl)-2-phenyl-pyrazolo[1,5-a]pyrimidine-7-carboxylic acid, methyl ester
Purity: ≥95%
Formula Markup: C21H15N3O4
Formula Weight: 373,4
Shelf life (days): 1460
CAS Number: 1011366-31-6
Notes: MCI-INI-3 is an inhibitor of aldehyde dehydrogenase 1A3 (ALDH1A3; Ki = 0.55 µM).{51921} It is selective for ALDH1A3 over ALDH1A1 (Ki = 78.2 µM). MCI-INI-3 (15 µM) inhibits the conversion of retinol to retinaldehyde in U87MG glioblastoma cells. It reduces the viability of GSC-83 and GSC-326 glioblastoma cells when used at a concentration of 15 µM.