Product Description: MELK is a multifunctional serine/threonine protein kinase that regulates the cell cycle, stem cell self-renewal, apoptosis, and splicing. MELK phosphorylates BCL2L14, CDC25B, MAP3K5/ASK1 and ZNF622, activates apoptosis through MAP3K5/ASK1, helps CDC25B localize during mitosis, and inhibits BCL2L14, which may affect breast cancer occurrence. MELK Protein, Human (His) is the recombinant human-derived MELK protein, expressed by E. coli , with N-6*His labeled tag. The total length of MELK Protein, Human (His) is 328 a.a., .
Formula: 9833(Gene_ID)Q14680 (D3-V330)(Accession)
Molecular Weight: 39.7 kDa
Compound Purity: 93.00