Mesothelin antibody (ZM25)

Clone Name: ZM25

Light Chain: Kappa

Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 69

Positive Control: Mesothelioma

Form: Liquid

Buffer (with preservative): Tris-HCl buffer, 0.2% BSA, 0.09% Sodium azide.

Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]

Uniprot ID: Q13421

Antigen Species: Human

Immunogen: Recombinant human mesothelin (MSLN) protein fragment (around aa 273-407)

Purification: Purified IgG

Conjugation: Unconjugated

Full Name: mesothelin

• Artikelnummer: GTX01742-500
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX01742-500
• Green Labware: Nein
• Verpackungseinheit: 500 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG2b
• Human Gene ID: 10232
• Wirt: Mouse