mGluR1/5 Antibody, Clone N75/33: PerCP

Mouse Anti-Rat mGluR1/5 Monoclonal IgG1

Target: mGluR5

Conjugate: PerCP

Product Type: Monoclonal

Clone Number: N75/33 (Formerly sold as S75-33)

Immunogen: Fusion protein amino acids 824-1203 (cytoplasmic C-terminus) of rat mGluR5b

Swiss-Prot: P31424

Purification: Protein G Purified

Storage Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated

Concentration: 1 mg/ml

Specificity: Detects ~130kDa (both mGluR1 and mGluR5).

Cellular Localization: Cell Membrane

Scientific Background: The AMPA receptor is a non-NMDA-type ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the CNS. AMPARs are composed of four types of subunits, designated as GluR1, GluR2, GluR3 and GluR4, which combine to form tetramers (1,2).

References: 1. Mayer M.L. (2005) Current Opinion in Neurobio. 15(3): 282-288.2. Keinane K., et al. (1990) Science. 249: 556-560.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSMC-407D-PCP
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SMC-407D-PCP
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunoprecipitation, Western Blotting, Immunohistochemistry, Immunocytochemistry
• Isotyp: IgG1
• Human Gene ID: 24418
• Wirt: Mouse