Solubility: May be dissolved in DMSO (15mg/mL); or water (1mg/mL, warm)
Appearance: Dark Purple Crystalline Solid
PubChem CID: 5746
Scientific Background: The mitomycins are a family of aziridine containing natural products. Mitomycin C is a chemotherapeutic agent because of its mechanism of potent DNA crosslinker, reductive activation followed by two N-alklyations. Both alkylations are sequence specific for a guanine nucleoside in the sequence 5'-CpG-3' (1).
References: 1. Tomasz M. (1995). Chem and Biol. 2(9): 575-579.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.