MLCK antibody (GT1296)

MLCK antibody (GT1296)
Artikelnummer
GTX03208-100
Verpackungseinheit
100 μl
Hersteller
GeneTex

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Clone Name: GT1296

Application Note: WB: 1:500 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 211

Form: Liquid

Buffer (with preservative): PBS, 0.05% BSA, 50% Glycerol, 0.02% Sodium azide.

Concentration: 0.65 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts. [provided by RefSeq, Jul 2008]

Uniprot ID: Q15746

Antigen Species: Human

Immunogen: A synthesized peptide derived from human Myosin light chain kinase.

Purification: Purified by affinity chromatography

Conjugation: Unconjugated

Full Name: myosin light chain kinase
Mehr Informationen
Artikelnummer GTX03208-100
Hersteller GeneTex
Hersteller Artikelnummer GTX03208-100
Green Labware Nein
Verpackungseinheit 100 μl
Mengeneinheit STK
Reaktivität Human, Mouse (Murine), Rat (Rattus)
Klonalität Monoclonal
Methode Western Blotting
Isotyp IgG
Human Gene ID 4638
Wirt Rabbit
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