MLKL antibody

Application Note: WB: 1:1000. IHC-P: 1:400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 54

Form: Liquid

Buffer (with preservative): PBS, 0.09% sodium azide.

Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)

Background: This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to lack protein kinase activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (Rip3), which is a key signaling molecule in necroptosis pathway. Knockout of this gene in mice showed that it is essential for necroptosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]

Uniprot ID: Q9D2Y4

Antigen Species: Mouse

Immunogen: KLH conjugated synthetic peptide between 444-472 amino acids from the C-terminal region of mouse Mlkl.

Purification: Protein A purified followed by antigen-affinity chromatography

Conjugation: Unconjugated

Full Name: mixed lineage kinase domain-like

• Artikelnummer: GTX03807-200
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX03807-200
• Green Labware: Nein
• Verpackungseinheit: 200 μl
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine)
• Klonalität: Polyclonal
• Methode: Immunohistochemistry (paraffin), Western Blotting
• Isotyp: IgG
• Human Gene ID: 74568
• Wirt: Rabbit