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Encompassing Amino Acids: 52-750(end)
Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Description: Human membrane metallo-endopeptidase (MME), also known as CALLA, neutral endopeptidase (NEP), CD10, and Neprilysin (GenBank Accession No. NM_000902.3), a.a. 52-750(end), with N-terminal His-tag, MW= 81kDa, expressed in HEK293 cell expression system.
Format: Aqueous buffer solution
Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 200 mM imidazole, and 20% glycerol
Genbank: NM_000902.3
Storage Stability: At least 6 months at -80°C.
Tags: N-terminal His-tag
Uniprot: P08473
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Zhou, L., et al., Am J Transl Res.2013 Sep 25;5(6):608-21.
2. Pereira, N.L., et al. J. Mol. CellCardiol. 2010 Nov;49(5):864-74.