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Applications: Great for studying enzyme kinetics and HTS applications.
Background: MMP2 (matrix metalloproteinase 2), also known as Gelatinase A, is a member of the matrix metalloproteinase (MMP) family involved in the breakdown of type IV collagen, a major structural component of basement membranes. The activity of MMP2 is associated with cancer cell metastasis and other diseases, including Multicentric Osteolysis, Nodulosis, and Arthropathy.
Description: The Fluorogenic MMP2 Assay Kit is designed to measure MMP2 activity for screening and profiling applications, in a homogeneous assay with no time-consuming washing steps.
Storage Stability: One year from date of receipt when stored as directed.
Supplied As: The kit comes in a convenient 96-well format, with purified MMP2 enzyme, fluorogenic substrate, and MMP2 assay buffer for 100 enzyme reactions.
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Bjorklund, M. and Koivunen, E. 2005 May 25; Biochimica et Biophysica Acta. 1755 (1): 37-69.
2. Olaf, R.F., et al. 2004 Dec 17; Biochimica et Biophysica Acta. 1705 (2): 69-89.