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Applications: Great for studying enzyme kinetics and HTS applications.
Background: MMP8 (matrix metalloproteinase 8) is a member of the matrix metalloproteinase (MMP) family involved in the degradation of the extracellular matrix. MMP8 is also associated with the regulation of cytokines and chemokines, suggesting a role for MMP8 in inflammation.
Description: The Fluorogenic MMP8 Assay Kit is designed to measure MMP8 activity for screening and profiling applications, in a homogeneous assay with no timeconsuming washing steps.
Storage Stability: One year from date of receipt when stored as directed.
Supplied As: The kit comes in a convenient 96-well format, with purified MMP8 enzyme, fluorogenic substrate, and MMP8 assay buffer for 100 enzyme reactions.
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Thirkettle S., et al., 2013 Jun 7. J Biol Chem. 288(23): 16282-16294.
2. Dejonckheere E, et al., 2011 Apr. Cytokine Growth Factor Rev. 22(2):73-81.