Mouse anti-ABRA1 Purified, clone ABRA1-01 (Monoclonal)

Clone Number: ABRA1-01

Immunogen: Recombinant protein corresponding to amino acids 1-313 of ABRA1 with N-terminal His6 tag

Concentration: 1 mg/ml

Format: Purified by protein-A affinity chromatography.

Storage buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Additional info: ABRA1 (Abraxas), also known as CCDC98, is an adaptor protein that is essential for formation and function of BRCA1 A tumor suppressor complex. This complex plays critical roles in DNA repair, cell cycle checkpoint control, and maintenance of genomic stability. ABRA1 mediates interaction of ubiquitin-interacting motif-containing protein RAP80 and deubiquitination enzyme BRCC36 with BRCA1/BARD1. ABRA1 controls both DNA-damage-induced formation of BRCA1 foci and BRCA1-dependent G2/M checkpoint activation.SpecificityMouse monoclonal antibody AE1 recognizes acidic type cytokeratins (intracellular antigens), namely K10, 14, 15, 16, 19 (40-56 kDa). This antibody stains well the basal layer of epidermis and most epithelia.Application detailsFlow cytometry: Recommended dilution: 1-2 μg/ml. Intracellular staining.
Western blotting: Reducing conditions.

• Artikelnummer: SANMON23003
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON23003
• Green Labware: Nein
• Verpackungseinheit: 0,1 mg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunoprecipitation, Western Blotting, Flow Cytometry
• Isotyp: IgG
• Wirt: Mouse