Mouse anti-ALK Protein, clone ALK-1

Clone Number: ALK-1

Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers

Concentration: n/a

Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide

Additional info: Anaplastic lymphoma kinase (ALK) is a novel receptor protein-tyrosine kinase. ALK can create a fusion protein with a nuclear protein gene called nucleophosmin (NPM) via the amino terminus of NPM and the catalytic domain of ALK. The product of this fusion protein is oncogenic.1 Studies have found this chromosomal translocation in most anaplastic large-cell non-Hodgkin's lymphomas, making ALK a good marker for anaplastic large cell lymphomas

References: Iwahara T, et al. Oncogene. 1997; 14:439-49/Morris SW. Science. 1994; 263:1281-4

• Artikelnummer: SANMON-RTU1007
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON-RTU1007
• Green Labware: Nein
• Verpackungseinheit: 7 ml
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG1-k
• Wirt: Mouse