Clone Number: EBS-O-109
Immunogen: human PBL from a T-ALL patient
Concentration: 100 ug/ml
Storage buffer: PBS with 0.02% sodium azide
Additional info: EBS-O-109 reacts with human β-2 microglobulin, a 22 kDa protein, which associates noncovalently with the 44kDa α1-chain of the HLA Class I complex found on all nucleated cells and on platelets. There is no reaction with erythrocytes, neither with non-human primate cells. The detection of β-2 microglobulin in body fluids has been used as a tumor marker, renal failure marker and for monitoring patients with HIV infection.
References: Brodsky FM et al, lmmunol Rev 47: 3-61 (1979)/Ryschich, E, et al, Clin Cancer Res. 11(2 Pt 1): 498-504 (2005)/Cosgrove LJ, et al, Immunol. Cell Biol. 66 (1): 69-77 (1988)