Clone Number: 56C6
Immunogen: Recombinant protein encoding external domain of human CD10
Concentration: n/a
Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Additional info: Common acute lymphoblastic leukemia antigen (CALLA / CD10) is a useful marker for the characterization of childhood leukemia and B cell lymphomas. This antibody reacts with antigen of lymphoblastic, Burkitt’s, and follicular lymphomas; and chronic myelocytic leukemia. Also, Anti-CD10 detects the antigen of glomerular epithelial cells and the brush border of the proximal tubules; this characteristic may be helpful in interpreting renal ontogenesis in conjunction with other markers. Other non-lymphoid cells that are reactive with CD10 are breast myoepithelial cells, bile canaliculi, neutrophils and small population of bone marrow cells, fetal small intestine epithelium, and normal fibroblasts.
References: Maguer-Satta V, et al.. Stem Cells. 2011; 29:389-96/Laurent C, et al. 2010; 95: 356-8/Onak NK, et al.. Turk J Med Sci. 2010; 40:177-84