Mouse anti-CD11b, clone VIM12, R-PE (Monoclonal)

Clone Number: VIM12

Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers

Concentration: n/a

Storage buffer: PBS with 0.1% sodium azide

Additional info: CD11b (integrin alpha-M, ITGAM, integrin alpha-X, ITGAX) is a 165 kDa adhesion molecule that associates non-covalently with integrin beta-2 (CD18). The CD11b/CD18 heterodimeric complex is also known as integrin alpha-M beta-2, Mac-1, and CR3 (complement receptor 3). CD11b is expressed on the surface of monocytes/macrophages, granulocytes, activated lymphocytes, a subset of NK cells, a subset of dendritic cells, and microglia in the brain. CD11b/CD18 functions as the receptor for ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), CD14, CD50, CD23, heparin, iC3b, fibrinogen, and Factor X -these adhesions are critical for cell-cell and cell-matrix interactions.

References: Bi L. et al. Oncology letters 2018

• Artikelnummer: SANMON1019R
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON1019R
• Green Labware: Nein
• Verpackungseinheit: 0,5 ml
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Flow Cytometry
• Isotyp: IgG1
• Wirt: Mouse