Mouse anti-CD11b/CR3, clone BEAR-1 (Monoclonal)

Mouse anti-CD11b/CR3, clone BEAR-1 (Monoclonal)
Artikelnummer
SANMON1019-1
Verpackungseinheit
1 ml
Hersteller
Sanbio / Monosan

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Clone Number: BEAR-1

Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers

Concentration: 100 ug/ ml

Storage buffer: PBS with 0.1% BSA and 0.02% sodium azide

Additional info: CD11b is an alpha chain integrin that is expressed as heterodimer noncovalently associated with CD18. CD11b is also designated as CR3, Mac-1, Mo-1 in integrin alphaM subunit and has a molecular weight of 165-170 kDa. The protein mediates PMN and monocytes adherence to endothelium and subsequently PMN extravasation to sites of inflammation. CD11b/CD18 interacts with both matrix and cell surface proteins including the complement component iC3b, extracellular matrix proteins and the third extracellular domain of CD54. CD11b is expressed on human NK-cells, monocytes, granulocytes, T-cells, B-cells and dendritic cells. After activation the expression is upregulated. Bear-1 reacts with the CD11b alpha chain of the CD11b/CD18 (p165, 95) integrin heterodimer complex.

References: Keizer; G et al. Eur J Immunol 1985; 15: 1142 /Watanabe, A et al Int Arch Allergy Immunl 1992, 98: 308
Mehr Informationen
Artikelnummer SANMON1019-1
Hersteller Sanbio / Monosan
Hersteller Artikelnummer MON1019-1
Green Labware Nein
Verpackungseinheit 1 ml
Mengeneinheit STK
Reaktivität Human
Klonalität Monoclonal
Methode Immunohistochemistry (frozen), Immunoprecipitation, Flow Cytometry
Isotyp IgG1
Wirt Mouse
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