Mouse anti-CD147, clone CB43 (Monoclonal)

Clone Number: CB-43

Immunogen: Native leucocytes

Concentration: 100 ug/ml

Storage buffer: PBS with 0.02% sodium azide

Additional info: CD147 is a transmembrane glycoprotein of the immunoglobulin superfamily. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is involved in the regulation of matrix remodeling at the epidermal-dermal interface. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes, which are typically increased during tissue degradation and wound healing, are important factors in cancer invasion and metastasis.

References: Kirsch AH et. al. Tissue Antigens 50(2): 147-52 (1997)

• Artikelnummer: SANMON2034
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON2034
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunohistochemistry (frozen), Flow Cytometry
• Isotyp: IgM
• Wirt: Mouse