Mouse anti-CD16, clone 3G8, R-PE (Monoclonal)

Clone Number: 3G8

Conjugate: R-PE

Immunogen: Human CD16

Concentration: n/a

Storage buffer: PBS with 4mg/ml BSA and 0.1% sodium azide

Additional info: CD16 (FCGR3A) is a 50-65 kDa cell surface molecule that exists in two forms - a transmembranous form expressed by NK cells and some T cells, and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC by NK cells. Human CD16 is expressed in two forms – FCGR3A and FCGR3B. FCGR3A is associated with the FcepsilonRI-gamma subunit and is responsible for antibody-dependent NK cell cytotoxicity.

References: Smits SA et al. Front in Immunol 2019/Cepeda M et al. Tuberculosis 2013/He YY et al. Clin.Immunol 2012

• Artikelnummer: SANMON1187R
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON1187R
• Green Labware: Nein
• Verpackungseinheit: 0,5 ml
• Mengeneinheit: STK
• Reaktivität: Human, Rhesus Monkey (Primate)
• Klonalität: Monoclonal
• Methode: Flow Cytometry
• Isotyp: IgG1k
• Wirt: Mouse