Mouse anti-CD18, clone CLB-LFA-1/1, FITC (Monoclonal)

Clone Number: CLB-LFA-1/1

Conjugate: FITC

Immunogen: Human CD18

Concentration: n/a

Storage buffer: PBS with BSA and 0.1% sodium azide

Additional info: CD18 integrin beta 2 subunit is a 90 kDa type I transmembrane protein expressed on all leucocytes. CD18 can combine with integrin molecules CD11a-c to form heterodimers at the cell surface, and these heterodimers are known to participate in the process of cell adhesion as well as cell-surface mediated signaling. CD18 forms heterodimers with four types of CD11 molecule to constitute leukocyte (beta2) integrins: alphaLbeta2 (CD11a/CD18, LFA-1), alphaMbeta2 (CD11b/CD18, Mac-1, CR3), alphaXbeta2 (CD11c/CD18) and alphaDbeta2 (CD11d/CD18). In most cases, the response mediated by the integrin is a composite of the functions of its individual subunits, and these integrins are essential for proper leukocyte migration, mediating intercellular contacts.

References: Hajishengallis G et al. Clin.Diagn Lab.Immunol 2002

• Artikelnummer: SANMON1110F
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON1110F
• Green Labware: Nein
• Verpackungseinheit: 0,5 ml
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Flow Cytometry
• Isotyp: IgG1
• Wirt: Mouse