Mouse anti-CD20, clone 109-3C2 (Monoclonal)

Clone Number: 109-3C2

Immunogen: stimulated human leucocytes

Concentration: 100 ug/ml

Storage buffer: PBS with 0.02% sodium azide

Additional info: 109-3C2 binds with CD20 which is a 30/33 kDa non-glycosylated transmembrane phosphoprotein with three extensive hydrophobic regions. CD20 is involved in regulation of B-cell activation. It is expressed on the surface of all B-cells beginning at the pro-B phase (CD45R+, CD117+) and progressively increasing in concentration until maturity. Plasma cells are negative. CD20 is retained on many B-cell malignancies. CD20 positive cells are also sometimes found in cases of Hodgkin’s disease, myeloma, and thymoma. 109-3C2 has been clustered at IVth and Vth HLDA Workshops.

References: Knapp W. Leukocyte Typing IV, Oxford Univ. Press, (1989)/Schlossman SF et al. Leukocyte Typing V Oxford University Press: 342-352 (1995)

• Artikelnummer: SANMON9930
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON9930
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (frozen), Flow Cytometry, Functional Assay
• Isotyp: IgG3-K
• Wirt: Mouse