Clone Number: 15-2
Immunogen: Purified human mannose receptor
Concentration: 1 mg/ml
Storage buffer: PBS, pH 7.4, 15 mM sodium azide
Additional info: CD206 (macrophage mannose receptor, MMR), also known as mannose receptor C1 (MRC1), is a type I transmembrane glycoprotein serving as pattern recognition receptor for carbogydrate groups on the surface of bacteria, fungi and other pathogens. Expressed mainly on tissue macrophages and dendritic cells, CD206 mediates endocytosis of these pathogens and presentation of their antigens to the adaptive immune system. CD206 can also be detected in a soluble form in human plasma and is elevated in patients with acute sepsis.
References: Shan, M. et al. PLoS Pathog 2007; 3(11):e169