Clone Number: HIT2
Conjugate: FITC
Immunogen: Human CD38
Concentration: n/a
Storage buffer: PBS with 4mg/ml BSA and 0.1% sodium azide
Additional info: CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. CD38 functions as a multi-catalytic ectoenzyme serving as ADP-ribosyl cyclase, cyclic ADP-ribose hydrolase and possibly NAD+ glycohydrolase or as a cell surface receptor. Antibodies to CD38 are useful in subtyping of lymphomas and leukemias, detection of plasma cells (i.e. identification of myelomas), and as a marker for activated B and T cells.
References: de Oliveira AL et al. Immunol 2013/Zhang et al. Exp Hematol 2000/Grammer AC et al. J Immunol 1999