Mouse anti-CD4, clone 4B12 (monoclonal)

Clone Number: 4B12

Immunogen: Prokaryotic recombinant protein corresponding to the external domain of the CD4 molecule.

Concentration: Greater than or equal to 405 mg/L

Storage buffer: Tissue culture supernatant with sodium azide

Additional info: The CD4 molecule (T4) is a single chain transmembrane glycoprotein with a molecular weight of 59 kD. The CD4 antigen is expressed on a T cell subset (helper/inducer) representing 45% of peripheral blood lymphocytes and at a lower level on monocytes and germinal center macrophages. Most cases of cutaneous T cell lymphoma, including mycosis fungoides, express the CD4 antigen and HTLV-1 associated adult T cell leukemia/lymphoma is also generally CD4 positive.

References: Arnould L et al. British Journal of Cancer 2006; 94:259-267/Choi HJ et al. British Journal of Dermatology 2006; 154:419-425/Lapperre TS et al. Thorax 2006; 61:115-121

• Artikelnummer: SANMONX10329
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MONX10329
• Verpackungseinheit: 1 ml
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG1 kappa
• Wirt: Mouse
• Konjugat: Unconjugated