Mouse anti-CD44, clone NKI-P2 (Monoclonal)

Clone Number: NKI-P2

Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers

Concentration: 100 ug/ml

Storage buffer: PBS with 0.1% BSA and 0.02% sodium azide

Additional info: CD44, also designated Pgp-1 or H-CAM, is a broadly distributed 85 kD protein. Amongst haematopoietic cells CD44 is expressed on B and T lymphocytes, monocytes and neutrophils. Other CD44-positive cell types include epithelial cells, glial cells, fibroblasts and myocytes. This broad distribution suggest a general role in cell-cell and cell-matrix adhesion. CD44 is involved in T cell activation and adhesion. Triggering of CD44 increases homotypic T cell aggregation mediated via LFA-1. CD44 is linked to the cytoskeleton. Furthermore CD44 has an accessory role in lymphocyte adhesion to high endothelial venules.

References: Pals et al. J Immunol 1989;143:851/Pals et al. Blood 1989;73:885/Oostendorp et al/ Exp Hematol 1991;25:345

• Artikelnummer: SANMON1150
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON1150
• Green Labware: Nein
• Verpackungseinheit: 1 ml
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (frozen), Immunohistochemistry (paraffin), Flow Cytometry
• Isotyp: IgG1
• Wirt: Mouse