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Mouse anti-CD45RO Monoclonal Antibody, Purified (UCHL-1)
Mouse anti-CD45RO Monoclonal Antibody, Purified [UCHL-1]
Artikelnummer
BEYA500-020ACF
Verpackungseinheit
100 µl
Hersteller
Bethyl Laboratories
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Stock Concentration: 1000 µg/ml
Conjugate Type: Unconjugated
Buffer: Phosphate Buffered Saline (PBS) with 0.09% Sodium Azide, BSA-Free
Shelf Life: 1 year from date of receipt
Protein ID: NP_563578.2
Uniprot ID: P08575
Background: CD45RO is also known as protein tyrosine phosphatase receptor type C (PTPRC). It is a protein tyrosine phosphatase required for T-cell activation through the antigen receptor. CD45RO acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, CD45RO recruits and dephosphorylates SKAP1 and FYN. It also dephosphorylates LYN, and thereby modulates LYN activity (By similarity)[taken from UniProtKB (Entry: P08575)].
Immunogen: Cultured T-cells from an IL-2-dependent T-cell line (CA1)
Conjugate Type: Unconjugated
Buffer: Phosphate Buffered Saline (PBS) with 0.09% Sodium Azide, BSA-Free
Shelf Life: 1 year from date of receipt
Protein ID: NP_563578.2
Uniprot ID: P08575
Background: CD45RO is also known as protein tyrosine phosphatase receptor type C (PTPRC). It is a protein tyrosine phosphatase required for T-cell activation through the antigen receptor. CD45RO acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, CD45RO recruits and dephosphorylates SKAP1 and FYN. It also dephosphorylates LYN, and thereby modulates LYN activity (By similarity)[taken from UniProtKB (Entry: P08575)].
Immunogen: Cultured T-cells from an IL-2-dependent T-cell line (CA1)
| Artikelnummer | BEYA500-020ACF |
|---|---|
| Hersteller | Bethyl Laboratories |
| Hersteller Artikelnummer | A500-020ACF |
| Green Labware | Nein |
| Verpackungseinheit | 100 µl |
| Mengeneinheit | STK |
| Reaktivität | Human |
| Klonalität | Monoclonal |
| Methode | Immunofluorescence, Western Blotting, Flow Cytometry, Immunohistochemistry, Immunocytochemistry |
| Isotyp | Whole IgG |
| Human Gene ID | 5788 |
| Wirt | Mouse |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
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