Clone Number: MEM-118
Immunogen: HPB-ALL human T cell line
Concentration: 1 mg/ml
Storage buffer: Tris buffered saline (TBS) solution with 15 mM sodium azide
Additional info: CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade. Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can still regulate complement when bound to CD97. In tumours, besides protection agains complement, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis.