Clone Number: NK-1
Immunogen: preparation of HSB-2 T cell line
Concentration: n/a
Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Additional info: CD57, also known as HNK-1 (human natural killer-1), is a cell surface carbohydrate epitope expressed on terminally differentiated T-cells and subsets of natural killer (NK) cells.1 It has also been identified on cells of neural crest origin.2 Anti-CD57 is often used to visualize the non-neoplastic bystander T-cells that may form rosettes around the neoplastic lymphocyte-predominant (LP) cells in nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL).3
References: Kared H, et al. Cancer Immunol Immunother. 2016; 65:441-52/Nielsen CM, et al. Front Immunol. 2013; 4:422/Sattarzadeh A, et al. Exp Hematol Oncol. 2015; 4:27