Mouse anti-CD6, clone EBS-CD-005 (Monoclonal)

Clone Number: EBS-CD-005

Immunogen: human CD8+ human CTL clone

Concentration: 100 ug/ml

Storage buffer: PBS with 0.02% sodium azide

Additional info: EBS-CD-005 recognizes the CD6 molecule, a single chain transmembrane glycoprotein of 120 kDa, which is expressed on the majority of mature T-cells an mature thymocytes. A B-cell subset is weakly positive and B-CLL’s may also be reactive. CD6 is a type 1 transmembrane glycoprotein that is tyrosine phosphorylated during TCR-mediated T-cell activation. CD6 shows significant homology to CD5. Antibodies to CD6 are used to deplete T-cells from bone marrow transplants to prevent graft versus host disease.

References: Yssel et al., Cell. Immunol. 105: 161 (1987)/Kamoun et al., J. Immunol. 127: 987 (1981)/Reinherz et al., Proc. Nat. Acad. Sci. 79: 6047 (1982)

• Artikelnummer: SANMON9954
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON9954
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine)
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunohistochemistry (frozen), Flow Cytometry
• Isotyp: IgG1-k
• Wirt: Mouse