Mouse anti-CD61, clone EBS-CD-034 (Monoclonal)

Clone Number: EBS-CD-034

Immunogen: stimulated human PBMC’s

Concentration: 100 ug/ml

Storage buffer: PBS with 0.02% sodium azide

Additional info: EBS-CD-034 reacts with a complex of CD41 and CD61, i.e. alpha IIb integrin and the integrin beta chain. The MW of the GPIIIa is 105 kDa unreduced and 90 kDa reduced. The integrin beta 3 chain can also form a complex called the vitronectin receptor with integrin alpha V: the CD51/CD61 complex. Ligands are fibrinogen, fibronectin, von Willebrand factor, vitronectin and thrombospondin. Residues 237-248 of GPIIIa or CD61 are critical in adhesive protein binding. The CD51/CD61 complex is also found on endothelial cells, some B-cells, monocytes/macrophages and tumor cells.

References: Burns et al., Cell 45, 269 280 (1986)/McMichael AJ et al. (eds) Leukocyte Typing III, Oxford University Press, Oxford, (1987)/Schlossman S. et al. (eds) Leukocyte Typing V, Oxford University Press (1995)

• Artikelnummer: SANMON9955
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON9955
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunohistochemistry (frozen), Flow Cytometry
• Isotyp: IgM-k
• Wirt: Mouse