Mouse anti-CD8a, clone RIV11 (Monoclonal)

Clone Number: RIV11

Immunogen: human PBL

Concentration: 100 ug/ml

Storage buffer: PBS with 0.02% sodium azide

Additional info: RIV11 recognizes a protein of 32 kDa, identified as CD8a. The CD8 molecule consists of α and β chains, which are disulphide-linked into heterodimers or homodimers. CD8 is expressed on a T-cell subset (cytotoxic/suppressor T-cells), thymocytes and NK-cells. The majority of CD8+ T-cells express CD8 as heterodimer. Some subpopulations of CD8+ T-cells as well NK-cells may express homodimer. CD8 functions as a co-receptor in concert with TCR for binding the MHC class I/peptide complex. HIV-2 envelope glycoprotein binds CD8 α chain but not CD8 β chain.

References: Leerling et al, Communications RIV (1985)/Jonker et al, Transplantation 45: 677 (1988)

• Artikelnummer: SANMON9964
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON9964
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunohistochemistry (frozen), ELISA, Flow Cytometry
• Isotyp: IgG1-k
• Wirt: Mouse