Mouse anti-CD98, clone IPO-T10

Clone Number: IPO-T10

Immunogen: stimulated human PBL

Concentration: 100 ug/ml

Storage buffer: PBS with 0.02% sodium azide

Additional info: CD98 exists as a heterodimer containing a disulphide-linked glycosylated heavy chain and a nonglycosylated light chain. It is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through disulphide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intercellular calcium levels and transport L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized. Monocytes express high levels of CD98 antigen. Peripheral blood T- and B-cells, as well as NKcells and granulocytes express low levels of CD98. Activation of T-cells and NK-cells leads to upregulation of CD98. RBCs are negative. IPO-T10 was typed at the VIth International Workshop and Conference on Human Leukocyte Differentiation Antigens

References: The VIth International Workshop and Conference on Human Leukocyte Differentiation Antigens, Kobe, Japan (1996)/Woodhead VE et al. Int Immunol.12(7):1051-61 (2000)/Stonehouse TJ et al. Immunology 96: 35–47 (1999)

• Artikelnummer: SANMON2013
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON2013
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (frozen), Flow Cytometry
• Isotyp: IgM
• Wirt: Mouse