Mouse anti-Collagen Type IV, clone CIV22

Clone Number: CIV22

Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers

Concentration: n/a

Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide

Additional info: Collagen Type IV is the major component of the basal lamina so antibodies to this molecule confirm its presence and reveal the morphological appearance of the structure. Normal tissue stains with this antibody in a fashion consistent with the sites of mesenchymal elements and epithelial basal laminae. Anti-Collagen IV can also be useful in the classification of soft tissue tumors; schwannomas, leiomyomas. Their well differentiated, malignant counterparts usually immunoreact with this antibody. The vascular nature of neoplasms, hemangiopericytoma, angiosarcoma and epithelioid hemangioendothelioma can be revealed by this antibody with greater reliability than non-specific stains (e.g. silver reticulum).

References: Gould, VE, et al., Pathol Annul 1976;11:353-386/McArdle, JP, et al., Int J Cancer 1984;34:633-638/De Iorio P et al. Anticancer Res. 2001;21(2B):1395-9

• Artikelnummer: SANMON-RTU1066
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON-RTU1066
• Verpackungseinheit: 7 ml
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG1-k
• Wirt: Mouse
• Konjugat: Unconjugated