Mouse anti-Cyclin D1, clone P2D11F11 (monoclonal)

Clone Number: P2D11F11

Immunogen: Prokaryotic fusion protein corresponding to the human cyclin D1 molecule.

Concentration: Greater than or equal to 19 mg/L

Storage buffer: Tissue culture supernatant with Sodium azide

Additional info: The D-type cyclins are a family of proteins which function primarily by regulating the activity of cyclin dependent kinases in the G1 phase of the cell cycle. Cyclin D1, a protein of 36 kD, is also known as PRAD1 or bcl-1. Maximum expression of cyclin D1 occurs at a critical point in mid to late G1 phase of the cell cycle. The cyclin D1 gene, located on 11q13 has been reported to be overexpressed in mantle cell lymphomas due to the chromosomal translocation t(11;18).

References: McIntosh GG et al. Oncogene. 1995; 11:885–891/Saiz AD et al. Journal of Pathology. 2002; 198(2):157–162/Mommers ECM et al. Journal of Pathology. 2001; 194(3):327–333

• Artikelnummer: SANMONX10265
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MONX10265
• Green Labware: Nein
• Verpackungseinheit: 1 ml
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG2a
• Wirt: Mouse