Clone Number: D5/16B4 & 8G7G3/1
Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers
Concentration: n/a
Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Additional info: Anti-Cytokeratin 5 & 6 is a marker for eptihelioid mesotheliomas. Anti-Cytokeratin 5 & 6 stains the cytoplasm of such cells. Anti-TTF-1 stains the nuclei in the case of lung adenocarcinomas and is negative in nearly all mesotheliomas. The nuclear vs. cytoplasmic staining pattern of this cocktail can be useful in distinguishing between mesothelioma and adenocarcinoma of the lung.
References: Ordóñez NG. Am J Surg Pathol. 1998; 22:1215-21/Jang KY, et al. Anal Quant Cytol Histol; 2001; 23:400-4/Srodon M, et al. Hum Pathol. 2002; 33:642-5